Preface........................................................ vii
Editors ........................................................ ix
Contributors ................................................... xi
Chapter 1
An Introduction and Overview .................................... 1
Steven M. Colegate and Russell J. Molyneux
Chapter 2
Detection and Isolation of Bioactive Natural Products .......... 11
Emilio L. Ghlsalberti
Chapter 3
Nuclear Magnetic Resonance Spectroscopy: Strategies for Structural
Determination .................................................. 77
Lindsay T. Byrne
Chapter 4
Quantitative NMR of Bioactive Natural Products ................ 113
Guldo F. Pauli, Birgit U. Jakl, David C. Lankin, John A,
Walter, and Ian W. Burton
Chapter 5
Development and Application of LC-NMR Techniques to
the Identification of Bioactive Natural Products .............. 143
Jean-Luc Wolfender, Emerson F. Queiroz, and Kurt Hostettmann
Chapter 6
Determination of the Absolute Configuration of Bioactive Natural
Products Using Exciton Chirality Circular Dichroism ........... 191
Hans-Ulrich Humpf
Chapter 7
Separation of Enantiomeric Mixtures of Alkaloids and Their
Biological Evaluation .................................... .... 209
Stephen T. Lee, Russell J. Molyneux, and Kip E. Panter
Chapter 8
Dereplication and Discovery of Natural Products by UV
Spectroscopy .................................................. 221
Thomas O. Larsen and Michael A.E. Hansen
Chapter 9
Liquid Chromatography-Mass Spectrometry in Natural Product
Research ...................................................... 245
Ka-Wing Cheng, Feng Chen, and Mingfи Wang
Chapter 10
Application of High-Speed Countercurrent Chromatography to
the Isolation of Bioactive Natural Products ................... 267
Huabin Li and Feng Chen
Chapter 11
Biosensing Approach in Natural Product Research ............... 299
Maria Minunni and Anna R. Bilia
Chapter 12
Anticancer Drug Discovery and Development from Natural
Products ...................................................... 323
Gordon M. Cragg and David J. Newman
Chapter 13
Sourcing Natural Products from Endophytic Microbes ............ 371
Gary Strobel and Uvidelio Castillo
Chapter 14
Isolation of Bioactive Natural Products from Myxobacteria ..... 391
Makoto Ojika
Chapter 15
Naturally Occurring Glycosidase Inhibitors .................... 407
Robert J. Nash
Chapter 16
Bioassay-Directed Isolation and Identification of
Antiaflatoxigenic Constituents of Walnuts ..................... 421
Russell J. Molyneux, Noreen Mahoney, Jong H. Kim, and
Bruce C. Campbell
Chapter 17
Bioactive Peptides in Hen Eggs ................................ 439
Yoshinori Mine and Icy D 'Silva
Chapter 18
Biological Fingerprinting Analysis: Strategy for Screening
Bioactive Compounds in Traditional Chinese Medicines .......... 459
Xingye Su, Hanfa Zou, Xiaoyuan Lei, Liang Kong, and Lianghai Нu
Chapter 19
Antimalarial Compounds from Traditionally Used Medicinal
Plants ........................................................ 491
Lengo Mambu and Philippe Grellier
Chapter 20
Germination Stimulant in Smoke: Isolation and
Identification ................................................ 531
Gavin R. Flematti, Emilio L. Ghisalberti, Kingsley W. Dixon,
and Robert D. Trengove
Chapter 21
Plant-Associated Toxins: Bioactivity-Guided Isolation, ELISA,
and LC-MS Detection ........................................... 555
Steven M. Colegate
Index ......................................................... 585
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