Contents in Softstrip format i
Contributors to this issue 563
Graphical Abstracts 565
Studies on quinazolinones-III. Novel and efficient
route to the synthesis ofconformationally restricted
analogues of ketanserin and SGB-1534 as antihyper
tensive agents
J.-W.Cherin, C.-Y.Shiau and G.-Y.Lu 571
Synthesis of new disoxaril analogues with potene and
selective antihuman rhinovirus 14 activity
S.Massa, M.Artico, A.Mai, R.Ragno, F.Corelli,
A.Pani,M.E.Marongiu, E.Tramontato and P.La Colla 575
Synthesis and biological activity of galanthamine
derivatives as acetylcholinesterase (AChE) inhibitors
S.Y.Han, S.C.Mayer, E.J.Schweiger, B.M.Davis
and M.M.Joullie 579
A new potent inhibitor for angiotensin converting
enzyme: (R,S)-captopril-f3
I.Ojima and F.A.Jameison 581
Novel in vitro and in vivo inhibitors of profyl
endopeptidase
A.V.Bakker, J.Daffeh, S.Jung, L.A.Vincent, A.A.Nagel,
R.W.Spencer, F.J.Vinick and W.S.Faraci 585
Antihypertensive benzopyran-related potassium channel
activators: a role for lipophilicity
R.M.Soll, D.A.Quagliato, D.D.Deininger, P.J.Dollings,
B.L.Joslyn, T.M.Dolak, S.J.Lee, C.Bohan, A.Wojdan,
M.E.Morin and G.Oshiro 591
Syntesis and DNA binding properties of an amidine-linked
and phenil-containing analogue of distamiycin
A.M.Lee, L.A.White, J.A.Nobles, S.M.Forrow
and J.A.Hartley 595
A bioactive benzoindenone from Eichhornia crassipes
Solms
M.Della Greca, R.Lanzetta, L.Mangoni, P.Monaco
and L.Previtera 599
Biomimetic oxidation of 21-hydroxy, 21-formyl and
21-carboxilic pregn-4-en-3,20-dione with chemical
cytochrome P450 model systems
S.M.S.Chauhan and P.C.Ray 601
Trans-esterification reactions yield novel masked
phosphate derivates of the anti-cancer agent araC
C.McGuigan, B.C.N.M.Jones and P.A.Riley 607
5-(3-Carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-
3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and
related analogs of 3-(4,5-dimethylthiazolyl)-2,5-
diphenyltetrazolium bromide (MTT) reducing to purple
water-soluble formazans as cell-viability
indicators
J.A.Barltrop, T.C.Owen, A.H.Cory and J.G.Cory 611
A thiophosphate substrate for a continous spectro
photometric assay of phosphatidylinositol-
specific phospholipase C: hexadecylthiophosphoryl
-1- myo-inositol
E.K.Hendrickson, J.L.Johnson and H.S.Hendrickson 615
A fluorescent substrate for the assay of
phosphatidylinositol-specific phospholipase C:
4-(1-pyreno)butylphosphoryl-1-myo-inositol
E.K.Hendrickson, J.L.Johnson and H.S.Hendrickson 619
Synthesis and biological activity of fluorinated
intermediates of the methionine salvage pathway 623
Monodeoxy-1,4:3,6-dianhydrohexitol nitrates
P.Stross and S.Erhardt 629
New stereospecific syntheses of (E,E,Z)- and (E,E,E)-
10,12,14-hexadecatrienal, sex pheromonal components
of Manducta Sexta
F.Tellier 635
Linear sesterterpenes from the Caribbean sponge
Thorecta horridus with inflammatory activity
E.Fattorusso, V.Lanzotti, S.Magno, L.Mayol,
M.Di Rosa and A.Ialenti 639
A new class of leukotriene biosynthesis inhibitors:
the development of ((4-(4-chlorophenyl)-1-(4-(2-
quinolinylmethoxy)phenyl)-butyl)thio)acetic acid, L-674 636
P.Prasit, M.Belley, J.F.Evans, J.Y.Gauthier,
C.Leveille,C.S.McFarlane, E.Maclnytre, L.Peterson,
H.Piechuta,M.Therien, R.N.Young and R.Zamboni 645
Triply-convergent synthesis of a homochiral 3,3-
dymethyl,15-cyclohexyl prostacyclin analog
R.A.Berglund, T.F.Braish, J.A.Jakubowski
and P.L.Fuchs 649
Phosphonamidates and phosphonamidate esters as HIV-1
protease inhibitors
D.A.McLeod, R.I.Brinkworth, J.A.Ashley, K.D.Janda
and P.Wirschung 653
Instructions to Contributors i
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