Profiles of drug substances, excipients, and related methodology. Vol.33: Critical compilation of pKa values for pharmaceutical substances / Brittain H. - Amsterdam: Elsevier, 2007. - 774 p. - ISBN 978-0-12-260833-9; ISSN 0099-5428  Место хранения:   032 | Институт органической химии им. Н.Н.Ворожцова СО РАН | Новосибирск | Библиотека

Contents

Foreword ...................................................... vii Acknowledgments ................................................ ix Dedication ..................................................... xi Preface ...................................................... xiii Critical Compilation of pKa Values for Pharmaceutical Substances Richard J. Prankerd l Introduction ................................................. 1 2. Evaluation of Methods for pKa Determination .................. 7 3. pKa Values from Computer Programs ........................... 24 4. Summary of the Data Compilation ............................. 26 References ..................................................... 28 Data Compilations Appendix A Main List pKa Values Found with Significant Data Quality Information- Mainly Primary Literature ...................................... 35 Appendix B Supplementary List pKa Values Found with Little or No Data Quality Information-Mainly Secondary Literature ....................... 425 Index Alphabetical Index of Drugs or Drug Related Compounds Found in pKa Database Files ................................... 627 Subject Index ................................................. 725