Preface ...................................................... xiii
Frontiers in Neuroscience ...................................... xv
About the Editors ............................................ xvii
Contributors .................................................. xix
Chapter 1 The Amyloid β-Protein and Alzheimer's Disease ........ 1
David B. Teplow, Mingfeng Yang, Robin Roychaudhuri,
Eric Pang, Tien-Phat Huynh, Mei-Sha Chen, and
Shiela Beroukhim
Chapter 2 Emerging Principles and Biomarkers in In Vitro
Diagnostics for Alzheimer's Disease ................. 87
Renee D. Wegrzyn and Alan S. Rudolph
Chapter 3 Imaging Biomarkers for Diagnosis, Prognosis, and
Treatment of Alzheimer's Disease ................... 103
Daniel M. Skovronsky and Giora Z. Feuerstein
Chapter 4 The Current Status of Alzheimer's Disease
Treatment: Why We Need Better Therapies and How
We Will Develop Them ............................... 117
Krista L. Lanctôt, Ida Kircanski, Sarah A. Chau,
and Nathan Herrmann
Chapter 5 New Small Molecule Drug Discovery for
Alzheimer's Disease ................................ 163
Kangning Liu, Minhua Zhang, and Guhan Nagappan
Chapter 6 Alzheimer's Disease: Clinical Aspects .............. 211
R. Scott Turner
Chapter 7 Pathogenic Protein Strains as Diagnostic and
Therapeutic Targets in Alzheimer's Disease ......... 231
Lary C. Walker, Rebecca F. Rosen, and Harry
LeVine III
Chapter 8 Traumatic Brain Injury in the Development of
Alzheimer's Disease: Risk Factors, Diagnosis, and
Treatment Strategies ............................... 249
Mark P. Burns
Index ......................................................... 271
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