Molecular imaging with reporter genes / ed. by S.S.Gambhir, Sh.S.Yaghoubi. - Cambridge; New York: Cambridge University Press, 2010. - xiii, 321 p.: ill. (some col.). - (Cambridge molecular imaging series). - Incl. bibl. ref. - Ind.: p.315-321. - ISBN 978-0-521-88233-0  Место хранения:   05 | Сибирский институт физиологии и биохимии растений СО РАН | Иркутск

Оглавление / Contents

Contributors ................................................... ix Preface ...................................................... xiii Part I. Types of Imaging Reporter Genes 1 Fluorescent Reporter Proteins ................................ 3 Robert E. Campbell and Michael W. Davidson 2 Revealing Biomolecular Mechanisms Through In Vivo Bioluminescence Imaging ..................................... 41 Timothy C. Doyle, Qian Wang, and Christopher H. Contag 3 Reporter Gene Imaging with PET/SPECT ........................ 70 June-Key Chung, Joo Hyun Kang, and Keon Wook Kang 4 Noninvasive Imaging of Gene Expression with Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy ....... 88 Mark D. Paget and James P. Basilion Part II. Enhancing Reporter Gene Imaging Techniques 5 Multimodality Imaging of Reporter Genes .................... 113 Prima Ray and Sanjiv Sam Gambhir 6 Cell-Specific Imaging of Reporter Gene Expression Using a Two-Step Transcriptional Amplification Strategy ............ 127 Marxa L. Figueiredo, Sanjiv Sam Gambhir, Michael Carey, and Lily Wu Part III. Imaging Instrumentations 7 Physics, Instrumentation, and Methods for Imaging Reporter Gene Expression in Living Subjects ................ 151 Craig S. Levin Part IV. Current Applications of Imaging Reporter Genes 8 Reporter Gene Imaging of Cell Signal Transduction .......... 195 Tarik F. Massoud, Ramasamy Paulmurugan, Carmel Chan, Hua Fan-Minogue, and Sanjiv Sam Gambhir 9 Gene Therapy and Imaging of Transgene Expression in Living Subjects ............................................ 227 Shahriar S. Yaghoubi and Sanjiv Sam Gambhir 10 Imaging Regulation of Endogenous Gene Expression in Living Subjects ............................................ 239 Vladimir Ponomarev 11 Imaging Cell Trafficking and Immune Cell Activation Using PET Reporter Genes ......................................... 258 Evan D. Nair-Gill, Chengyi J. Shu, Isabel J. Hildebrandt, Dean 0. Campbell, Owen N. Witte, and Caius G. Radu 12 Imaging of Reporter Genes and Stem Cells ................... 275 Martin G. Rodriguez-Porcel and Sanjiv Sam Gambhir 13 Clinical Applications of Reporter Gene Technology .......... 297 Iván Peñuelas, Shahriar S. Yaghoubi, Felipe Prósper, and Sanjiv Sam Gambhir Index ......................................................... 315