Pecorino L. Molecular biology of cancer: mechanisms, targets, and therapeutics. - 2nd ed. - Oxford; New York: Oxford University Press, 2008. - xviii, 316 p.: ill. (some col.). - Incl. bibl. ref. - Ind.: p.211-316. - ISBN 978-0-19921148-7  Место хранения:   06 | Якутский научный центр СО РАН | Якутск | Центральная научная библиотека Якутского научного центра СО РАН

Оглавление / Contents

PREFACE ....................................................... vii ACKNOWLEDGMENTS ................................................ xi 1 Introduction ................................................. 1 2 DNA structure and stability: mutations versus repair ........ 21 3 Regulation of gene expression ............................... 47 4 Growth factor signaling and oncogenes ....................... 69 5 The cell cycle .............................................. 95 6 Growth inhibition and tumor suppressor genes ............... 113 7 Apoptosis .................................................. 137 8 Stem cells and differentiation ............................. 161 9 Metastasis ................................................. 185 10 Infections and inflammation ................................ 211 11 Nutrients, hormones, and gene interactions ................. 231 12 The cancer industry: drug development and clinical trial design ..................................................... 259 13 Cancer in the future: focus on diagnostics and immunotherapy .............................................. 275 APPENDIX 1: CELL CYCLE REGULATION ............................. 297 APPENDIX 2: CENTERS FOR CANCER RESEARCH ....................... 298 GLOSSARY ...................................................... 302 INDEX ......................................................... 311