Statistical Estimation of Uncultivated Microbial Diversity ...... 1
J. Bunge
Characterizing Microbial Population Structures through
Massively Parallel Sequencing .................................. 19
Mitchell L. Sogin
Detection and Characterization of Uncultivated Microorganisms
Using Microarrays .............................................. 35
Terry J. Gentry, Zhili He, and Jizhong Zhou
The Seabed as Natural Laboratory: Lessons From Uncultivated
Methanotrophs .................................................. 59
Antje Boetius, Thomas Holler, Katrin Knittel, Janine
Felden, and Frank Wenzhöfer
Single Cell Whole Genome Amplification of Uncultivated
Organisms ...................................................... 83
Mircea Podar, Martin Keller, and Philip Hugenholtz
Physiological and Ecological Adaptations of Slow-Growing,
Heterotrophic Microbes and Consequences for Cultivation ....... 101
Thomas M. Schmidt and Allan E. Konopka
Viable but Not Cultivable Bacteria ............................ 121
Rita R. Colwell
General Model of Microbial Uncultivability .................... 131
Slava S. Epstein
Metagenomics and Antibiotic Discovery from Uncultivated
Bacteria ...................................................... 161
Vivian Miao and Julian Davies
Persisters, Biofilms, and the Problem of Cultivability ........ 181
Kim Lewis
Taking the Concept to the Limit: Uncultivable Bacteria
and Astrobiology .............................................. 195
Kenneth Nealson
Index ......................................................... 205
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