Lundblad R.L. Biotechnology of plasma proteins. - Boca Raton: CRC/Taylor & Francis, 2013. - (Protein science series). - Bibliogr. at the end of the chapters. - Ind.: p.441-446. - ISBN 978-1-4398-5026-8 Шифр: (И/Р26-L96) 02  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Preface ........................................................ ix Acknowledgments ................................................ xi Author ....................................................... xiii Chapter 1 Blood, Plasma, Cells, and Other Biological Fluids .... 1 Chapter 2 Plasma Fractionation and Plasma Protein Products .... 19 Chapter 3 Methods for the Analysis of Plasma and Plasma Protein Fractions ........................................... 47 Chapter 4 Albumin ............................................. 83 Structure of Albumin ........................................ 86 In Vitro Chemical Modification of Albumin .................. 101 Albumin as a Carrier ....................................... 113 Ligand-Binding by Albumin .................................. 121 Purification and Characterization of HSA for Clinical Use .. 123 Biological Activity of Albumin ............................. 125 Enzymatic Activity of Albumin .............................. 126 Clinical Use of Albumin .................................... 129 Albumin as Diagnostic/Biomarker ............................ 132 Pharmacokinetics of Albumin ................................ 133 Analytical Methods for Albumin Including Use of Albumin as Standard for Analytical Methods ......................... 134 Albumin as Excipient ....................................... 136 Conclusion ................................................. 136 References ................................................. 136 Chapter 5 Plasma Immunoglobulins ............................. 183 Chapter 6 Factor VIII and von Willebrand Factor .............. 233 von Willebrand Factor ...................................... 253 Economic Issues Impacting the Hemophilia Business .......... 255 Conclusions and Future Directions .......................... 257 References ................................................. 257 Chapter 7 Plasma Proteinase Inhibitors ....................... 285 Antithrombin ............................................... 285 α1,-Antitrypsin (a,-Antiprotease Inhibitor, SERPINA1) ...... 293 Heparin Cofactor II (SERPIND1) ............................. 301 α2-Macroglobulin ........................................... 301 Tissue Factor Pathway Inhibitor ............................ 304 α2-Antiplasmin ............................................. 311 C1-Inhibitor (C1-Esterase Inhibitor) ....................... 315 Plasminogen Activator Inhibitor-1 .......................... 319 Protein С Inhibitor (Plasminogen Activator Inhibitor-3) .... 322 References ................................................. 323 Chapter 8 Vitamin K-Dependent Proteins ....................... 367 Chapter 9 Miscellaneous Plasma Proteins ...................... 401 Fibrinogen ................................................. 401 Fibrin Sealant ............................................. 402 Autologous Fibrin Sealant .................................. 408 Fibrinogen and Tissue Soldering ............................ 408 Thrombin and Fibrin Foam ................................... 410 Fibrinogen Plastics ........................................ 411 Thrombin ................................................... 412 Plasminogen and Plasmin .................................... 412 Butyrylcholinesterase ...................................... 415 Fibronectin ................................................ 415 References .................................................... 417 Index ......................................................... 441