Chembiomolecular science: at the frontier of chemistry and biology: [the Uehara Memorial Foundation symposium - 2011] / eds.: M.Shibasaki, M.Iino, H.Osada - Tokyo: Springer, 2013. - xvi, 325 p.: ill. - Bibliogr. at the end of the art. - Ind.: p.321-325. - ISBN 978-4-431-54037-3  Место хранения:   02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents

Part I Chembiomolecular Chemistry Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer ........................................................... 3 Yoshito Kishi Practical Synthesis of Tamiflu and Beyond ...................... 15 Motomu Kanai An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis .......................... 23 Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai, Futoshi Hasegawa, Takeharu Nakashima, Nobuaki Matsumori, and Michio Murata Inhibitors of Fatty Acid Amide Hydrolase ....................... 37 Dale L. Boger Small Molecule Tools for Cell Biology and Cell Therapy ......... 51 Motonari Uesugi Toward the Discovery of Small Molecules Affecting RNA Function ....................................................... 59 Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi, Asako Murata, Masaki Hagihara, and Kazuhiko Nakatani New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases ................................................... 69 Go Hirai, Ayako Tsuchiya, and Mikiko Sodeoka The Deep Oceans as a Source for New Treatments for Cancer ...... 83 William Fenical, James J. La Clair, Chambers C. Hughes, Paul R. Jensen, Susana P. Gaudêncio, and John B. MacMillan Search for New Medicinal Seeds from Marine Organisms ........... 93 Motomasa Kobayashi, Naoyuki Kotoku, and Masayoshi Arai Identification of Protein-Small Molecule Interactions by Chemical Array ................................................ 103 Hiroyuki Osada and Siro Simizu Part II Chembiomolecular Biology Small Molecule-Induced Proximity .............................. 115 Fu-Sen Liang and Gerald R. Crabtree High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing .................................. 127 Erik S. Anderson, Peter Stoilov, Robert Damoiseaux, and Douglas L. Black Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans ....... 139 Masaharu Uno, Sakiko Honjoh, and Eisuke Nishida Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis ................................................. 145 Miki Kamiyama, Takehiro Sato, Kohsuke Takeda, and Hidenori Ichijo Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal ........................................ 155 Laura L. Kiessling Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis .................................................... 167 Reiji Kannagi, Keiichiro Sakuma, and Katsuyuki Ohmori Establishment of a Novel System for Studying the Syk Function in В Cells ........................................... 177 Tomohiro Kurosaki and Clifford A. Lowell Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures ............... 183 Kaya Shigaki, Kazuaki Tokunaga, Yuki Mihara, Yota Matsuo, Yamato Kojimoto, Hiroaki Yagi, Masayuki Igarashi, and Tokio Tani Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases ...................................................... 193 Shinji Oki, Benjamin J.E. Raveney, Yoshimitsu Doi, and Takashi Yamamura Antiviral MicroRNA ............................................ 201 Ryota Ouda and Takashi Fujita Synaptic Function Monitored Using Chemobiomolecular Indicators .................................................... 207 Masamitsu Iino Part III Chembiomolecular Medicinal Chemistry Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate ..................................................... 219 Masakatsu Shibasaki Hunting the Targets of Natural Product-Inspired Compounds ..... 229 Slava Ziegler and Herbert Waldmann Chemical Approaches for Understanding and Controlling Infectious Diseases ........................................... 239 Hirokazu Arimoto Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-γ Agonists ....................... 249 Hiroyuki Miyachi Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase ............................................. 261 Mark von Itzstein Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases ..................... 269 Kunihiko Nishino Enzymes as Chemotherapeutic Agents ............................ 281 Ronald T. Raines Mechanism of Action of New Antiinfectious Agents from Microorganisms ................................................ 293 Nobuhiro Koyama and Hiroshi Tomoda Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease ..... 301 Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, C. Frank Bennett, and Adrian R. Krainer Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications ..................... 315 Masatoshi Hagiwara Index ......................................................... 321