Neuroproteomics: methods and protocols / ed. by A.K.Ottens, K.K.W.Wang. - New York: Humana; London: Springer, 2009. - xi, 321 p.: ill. - (Springer protocols) (Methods in molecular biology; 566). - Incl. bibl. ref. - Ind.: p.315-321. - ISSN 1064-3745; ISBN 978-1-934115-84-8  Место хранения:   056 | Институт химической биологии и фундаментальной медицины CO РАН | Новосибирск| Библиотека

Оглавление / Contents

Preface ......................................................... v Contributors ................................................... ix 1 The Methodology of Neuroproteomics ........................... 1 Andrew K. Ottens Part I Disease Models in Neuroproteomics 2 Modeling Cerebral Ischemia in Neuroproteomics ............... 25 Jitendra R. Dave, Anthony J. Williams, Changping Yao, X.-C. May Lu, and Frank С. Tortella 3 Clinical and Model Research of Neurotrauma .................. 41 András Büki, Erzsébet Kövesdi, József Pál, and Endre Czeiter 4 Neuroproteomic Methods in Spinal Cord Injury ................ 57 Anshu Chen and Joe E. Springer 5 Modeling Substance Abuse for Applications in Proteomics ..... 69 Scott E. Hemby and Nilesh Tannu 6 Protein Aggregate Characterization in Models of Neurodegenerative Disease ................................... 85 Andrew T.N. Tebbenkamp and David R. Borchelt Part II Sub-Proteome Separations and Neuroproteomic Analysis 7 Sub-Proteome Processing: Isolation of Neuromelanin Granules from the Human Brain ............................... 95 Florian Tribl 8 Proteomic Analysis of Protein Phosphorylation and Ubiquitination in Alzheimer's Disease ...................... 109 Stefani N. Thomas, Diane Cripps, and Austin J. Yang 9 Proteomics Identification of Carbonylated and HNE-Bound Brain Proteins in Alzheimer's Disease ...................... 123 Rukhsana Sultana and D. Allan Butterfield 10 Mass Spectrometric Identification of In Vivo Nitrotyrosine Sites in the Human Pituitary Tumor Proteome ................................................... 137 Xianquan Zhan and Dominic M. Desiderio 11 Improved Enrichment and Proteomic Analysis of Brain Proteins with Signaling Function by Heparin Chromatography ............................................. 165 Kurt Krapfenbauer and Michael Fountoulakis 12 Calmodulin-Binding Proteome in the Brain ................... 181 Zhiqun Zhang, Firas H. Kobeissy, Andrew K. Ottens, Juan A. Martinez, and Kevin K.W. Wang Part III Neuroproteomic Methodology and Bioinformatics 13 Separation of the Neuroproteome by Ion Exchange Chromatography ............................................. 193 Brian F. Fuller and Andrew K. Ottens 14 iTRAQ-Based Shotgun Neuroproteomics ........................ 201 Tong Liu, Jun Нu, and Hong Li 15 Methods in Drug Abuse Neuroproteomics: Methamphetamine Psychoproteome ............................................. 217 Firas H. Kobeissy, Zhiqun Zhang, Shankar Sadasivan, Mark S. Gold, and Kevin K.W. Wang 16 Shotgun Protein Identification and Quantification by Mass Spectrometry in Neuroproteomics ....................... 229 Bingwen Lu, Tao Xuy Sung Kyu Park, Daniel B. McClatchy, Lujian Liao, and John R. Yates, III Part IV Biofluid Analysis and Clinical Translation 17 Identification of Glycoproteins in Human Cerebrospinal Fluid ...................................................... 263 Hye Jin Hwang, Thomas Quinn, and Jing Zhang 18 Mass Spectrometric Analysis of Body Fluids for Biomarker Discovery .................................................. 277 David M. Good and Joshua J. Coon 19 Traumatic Brain Injury Biomarkers: From Pipeline to Diagnostic Assay Development ............................... 293 Monika W. Oli, Ronald L. Hayes, Gillian Robinson, and Kevin K.W. Wang 20 Translation of Neurological Biomarkers to Clinically Relevant Platforms ......................................... 303 Ronald L. Hayes, Gillian Robinson, Uwe Muller, and Kevin K.W. Wang Index ......................................................... 315