Prologue by Ahmed H. Zewail .................................... xi
Chapter 1. The Preoccupations of Twenty-First-Century
Biology .............................................. 1
David Baltimore
Chapter 2. The World as Physics, Mathematics and Nothing Else ... 7
Alexander Varshavsky
Chapter 3. Physical Biology: 4D Visualization of Complexity .... 23
Ahmed H. Zewail
Chapter 4. Revolutionary Developments from Atomic to
Extended Structural Imaging ......................... 51
John Meurig Thomas
Chapter 5. Physical Biology at the Crossroads ................. 115
Carlos J. Bustamante
Chapter 6. The Challenge of Quasi-Regular Structures
in Biology ......................................... 137
Roger D. Kornberg
Chapter 7. The Future of Biological X-Ray Analysis ............ 145
Douglas C. Rees
Chapter 8. Reinterpreting the Genetic Code: Implications
for Macromolecular Design, Evolution and
Analysis ........................................... 165
David A. Tirrell
Chapter 9. Designing Ligands to Bind Tightly to Proteins ...... 189
George M. Whitesides, Phillip W. Snyder,
Demetri T. Moustakas, and Katherine A. Mirica
Chapter 10.Biology by the Numbers ............................. 217
Rob Phillips
Chapter 11.Eppur si muove ..................................... 247
Michele Parrinello
Chapter 12.Protein Folding and Beyond: Energy Landscapes
and the Organization of Living Matter in Time
and Space .......................................... 267
Peter G. Wolynes
Chapter 13.Protein Folding and Misfolding: From Atoms to
Organisms .......................................... 289
Christopher M. Dobson
Chapter 14.A Systems Approach to Medicine Will Transform
Healthcare ......................................... 337
Leroy Hood
Chapter 15.The Neurobiology of Consciousness .................. 367
Christof Koch and Florian Mormann
Chapter 16.Computer-Aided Drug Discovery: Physics-based
Simulations from the Molecular to the Cellular
Level .............................................. 401
J. Andrew McCammon
Chapter 17.Precision Measurements in Biology .................. 411
Stephen R. Quake
Chapter 18.Potassium Channels and the Atomic Basis of
Selective Ion Conduction ........................... 431
Roderick MacKinnon
The 2007 Welch Award Papers ................................... 463
Chapter 19.Symmetry Breaking, Delocalization and Dynamics
in Electron Transfer Systems ....................... 465
Noel S. Hush
Chapter 20.The Initial Value Representation of
Semiclassical Theory: A Practical Way for
Adding Quantum Effects to Classical Molecular
Dynamics Simulations of Complex Molecular
Systems ............................................ 505
William H. Miller
Biographies ................................................... 527
|
